A
aaankaa
⚪
уважаемая Ирина!
Похоже, что мы говорим на разных языках: не понимаю, почему при высокой вероятности наличия у Вас коагуляционных отклонений, Вы упорно ищете какие-то микробы, ответственные за невынашивание. Лучше бы вкладывались в более детальную верификацию этих нарушений или же закупили НМГ. Ureaplasma species - это "виды уреаплазм", дословный перевод. Для уреаплазмоза как механизма невынашивания необходимо выявление их колоний из шейки матки или эндометрия, а не просто их наличие, тем более выявление в моче у мужа методом ПЦР.
Согласно недавнему исследованию в Индии с не слишком развитым уровнем медицины антикардиолипиновые АТ IgG в высоком титре выявляются у каждой третьей с хронич. невынашиванием в первом триместре:
Med Sci Monit. 2003 Jun;9(6):CR213-6.
Prevalence of anticardiolipin antibody IgG in recurrent first trimester abortions and the role of aspirin in its prevention.
Kalra S, Tuli A, Choudhry R, Raheja S.
Departments of Anatomy and Obstetrics & Gynaecology, Lady Hardinge Medical College and associated hospitals, New Delhi, India.
BACKGROUND: Approximately 10% of all human pregnancies end in spontaneous abortions. In the majority of such cases the etiology remains unknown, but anticardiolipin antibodies are gaining recognition as potential causes of recurrent miscarriage. MATERIAL/METHODS: The prevalence of anticardiolipin antibody IgG (IgGacl) in 60 pregnant patients with recurrent first trimester abortions and 60 pregnant controls of comparable age with no history of abortion were examined to find a possible relation between IgGacl and spontaneous abortion. The assay for IgGacl was done by Enzyme Linked Immunosorbent Assay (ELISA). Positive test results were considered 'strongly elevated' with IgGacl levels exceeding 36 GPL units. Aspirin (80 mg per day) was prescribed for patients with recurrent first trimester abortion and strongly elevated levels of IgGacl. RESULTS: Strongly elevated levels of IgGacl were detected in a total of 18 patients (30%) with recurrent abortions, and none of the controls (p<0.001). Of all the patients with strongly elevated levels, 16 patients had unexplained abortions and 2 had explicable abortions. The relative risk for strongly elevated IgGacl was 3.78. These 16 patients with unexplained abortions were treated with aspirin, 80 mg per day, and a successful pregnancy outcome was observed in 10 patients, while 2 patients were in the third trimester of pregnancy. CONCLUSIONS: IgGacl is strongly associated with first trimester recurrent abortions and increases the risk approximately 4-fold. Aspirin is beneficial in patients with recurrent first trimester abortions and strongly elevated levels of IgGacl.
Похоже, что мы говорим на разных языках: не понимаю, почему при высокой вероятности наличия у Вас коагуляционных отклонений, Вы упорно ищете какие-то микробы, ответственные за невынашивание. Лучше бы вкладывались в более детальную верификацию этих нарушений или же закупили НМГ. Ureaplasma species - это "виды уреаплазм", дословный перевод. Для уреаплазмоза как механизма невынашивания необходимо выявление их колоний из шейки матки или эндометрия, а не просто их наличие, тем более выявление в моче у мужа методом ПЦР.
Согласно недавнему исследованию в Индии с не слишком развитым уровнем медицины антикардиолипиновые АТ IgG в высоком титре выявляются у каждой третьей с хронич. невынашиванием в первом триместре:
Med Sci Monit. 2003 Jun;9(6):CR213-6.
Prevalence of anticardiolipin antibody IgG in recurrent first trimester abortions and the role of aspirin in its prevention.
Kalra S, Tuli A, Choudhry R, Raheja S.
Departments of Anatomy and Obstetrics & Gynaecology, Lady Hardinge Medical College and associated hospitals, New Delhi, India.
BACKGROUND: Approximately 10% of all human pregnancies end in spontaneous abortions. In the majority of such cases the etiology remains unknown, but anticardiolipin antibodies are gaining recognition as potential causes of recurrent miscarriage. MATERIAL/METHODS: The prevalence of anticardiolipin antibody IgG (IgGacl) in 60 pregnant patients with recurrent first trimester abortions and 60 pregnant controls of comparable age with no history of abortion were examined to find a possible relation between IgGacl and spontaneous abortion. The assay for IgGacl was done by Enzyme Linked Immunosorbent Assay (ELISA). Positive test results were considered 'strongly elevated' with IgGacl levels exceeding 36 GPL units. Aspirin (80 mg per day) was prescribed for patients with recurrent first trimester abortion and strongly elevated levels of IgGacl. RESULTS: Strongly elevated levels of IgGacl were detected in a total of 18 patients (30%) with recurrent abortions, and none of the controls (p<0.001). Of all the patients with strongly elevated levels, 16 patients had unexplained abortions and 2 had explicable abortions. The relative risk for strongly elevated IgGacl was 3.78. These 16 patients with unexplained abortions were treated with aspirin, 80 mg per day, and a successful pregnancy outcome was observed in 10 patients, while 2 patients were in the third trimester of pregnancy. CONCLUSIONS: IgGacl is strongly associated with first trimester recurrent abortions and increases the risk approximately 4-fold. Aspirin is beneficial in patients with recurrent first trimester abortions and strongly elevated levels of IgGacl.